Scrub typhus is an acute febrile illness caused by orientia tsutsugamushi, transmitted to humans by the bite of the larva of trombiculid mites. It affects people of all ages. After an incubation period of 6-21 days, onset is characterized by fever, headache, myalgia, cough, and gastrointestinal symptoms. A primary papular lesion which later crusts to form a flat black eschar, may be present. If untreated, serious complications may occur involving various organs. Laboratory studies usually reveal leukopenia, thrombocytopenia, deranged hepatic and renal function, proteinuria and reticulonodular infiltrate. In this article we intend to describe the epidemiological and clinical profile of the patients suffering from scrub typhus as a cause of acute undifferentiated febrile illness.

Acute Undifferentiated Febrile syndromes (such as fever-rash, fever-myalgia, fever-arthralgia, fever-hemorrhage, and fever-jaundice) have overlapping etiologies, which makes their diagnosis and management even more challenging. The purpose of this article was to describe the clinical, laboratory, serological and radiological features of Enteric Fever as a cause of Acute Undifferentiated Febrile Illness among the patients admitted in the Department of Medicine at Indira Gandhi Medical College, Shimla, Himachal Pradesh, India. the mean age of the study participants suffering from enteric fever was found to be 28.1 days. Among all the patients of enteric fever, only 19% of the individuals suffered from arthralgia various 38% of the individual suffered from myalgia,22% of the individuals presented with nausea and vomiting and 6% of the individuals had the retrobulbar pain at the time of admission.

Preventive chemotherapy is the use of medicines, either alone or in combination, to prevent malaria infections and their consequences. It includes chemoprophylaxis, intermittent preventive treatment of infants (IPTi) and pregnant women (IPTp), seasonal malaria chemoprevention (SMC) and mass drug administration (MDA). These safe and cost-effective strategies are intended to complement ongoing malaria control activities, including vector control measures, prompt diagnosis of suspected malaria, and treatment of confirmed cases with antimalarial medicines. In this article, we describe the chemoprphylaxis recommended for the special population groups. In addition, we also discuss the challenges and opportunities that lie ahead of us in order to tackle malaria.