This study aims to examine the effect of organizational culture, work discipline, and human relations with organizational commitment as a mediating variable on the performance of UIN KHAS Jember lecturers. The population of this research is all lecturers of UIN khas Jember totaling 298 lecturers with sampling techniqueProportionate Stratified Random Sampling. This study uses a questionnaire distributed to lecturers via a google form. Data analysis method using SmartPLS. The results of this study indicate that organizational culture variables affect organizational performance and commitment, work discipline affects organizational performance and commitment, human relations affect organizational performance and commitment, and organizational commitment affects lecturer performance at UIN KHAS Jember.